Evolutionary-inspired probabilistic search for enhancing sampling of local minima in the protein energy surface
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چکیده
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EVOLVING LOCAL MINIMA IN THE PROTEIN ENERGY SURFACE by
EVOLVING LOCAL MINIMA IN THE PROTEIN ENERGY SURFACE Brian S Olson, PhD George Mason University, 2013 Dissertation Director: Dr. Amarda Shehu Proteins are the molecular tools of living cells and the path to unraveling their function is through modeling and understanding their structure. Many diseases occur when a protein loses its intended function due to inability to form the appropriate struct...
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ژورنال
عنوان ژورنال: Proteome Science
سال: 2012
ISSN: 1477-5956
DOI: 10.1186/1477-5956-10-s1-s5